We help clients assess chemical compound safety to develop safer and more effective pharmaceuticals, food ingredients, agricultural chemicals, commodity chemicals, and consumer products. At the frontline of next generation risk assessment (NGRA), we develop customized cell-based assays to determine safety, model chemical disposition in the body, and analyze and interpret genetic data. Our solutions save our clients time and money by bringing their products to market faster.
Latest News (See all)
Congratulations to Jake Reske! His abstract on transcriptomic predictive modeling for drug-induced cholestasis with ScitoVation was selected as a finalist for the Environmental Mutagenesis and Genomics Society Bioinformatics Challenge 2021.
Thanks to all who joined us on Tuesday, Mar. 30, for a special review of how PBPK modeling can be successfully applied to pesticide risk assessment, presented by Dr. Cecilia Tan, of the US EPA Office of Pesticide Programs. If you missed it, you may view the recording.
ScitoVation and BioSpyder are excited to introduce our new transcriptomics analysis package, ScitoXpress™. ScitoXpress™ provides important information about points of departure (POD) and potential modes of action (MoA) for our clients’ compounds. ScitoXpress™ characterizes chemical risk cost-efficiently and rapidly.
Because changes in gene expression precede changes in phenotype, a robust transcriptomics package like ScitoXpress™ can provide answers at lower doses compared to disease or tumor endpoints are typical used in in vivo studies. ScitoXpress™ offers the additional advantages of:
- Providing utility in guiding additional studies, resulting in cost- and time-savings
- Being based on a rigorous scientific approach, applied by experts
- Having the support of U.S. EPA
Who We Serve
By combining modern biological and computational methods, we help our clients develop safer and more effective pharmaceuticals, food ingredients, agricultural chemicals, commodity chemicals and consumer products.
Using Physiologically Based Pharmacokinetic (PBPK) Modeling and In vitro to In vivo Extrapolation (IVIVE) in Risk Assessment
To kick off a new year and decade, we assessed ScitoVation’s current and prospective positioning in the risk assessment community. As part of that process, the leadership team reviewed our… Read more »
By Mel Andersen, Ph.D., Senior Program Advisor It’s a grand time to be a toxicologist committed to using non-animal based biological and computational methods to assess the safety of chemicals and chemical products for human populations. My toxicology career… Read more »