ScitoVation transforms complex, fragmented toxicology data into clear, defensible safety decisions.

Computational toxicology that drives better, faster results.
ScitoVation helps chemical, pharmaceutical, consumer-product, and regulatory teams reach human-relevant conclusions faster and with greater scientific confidence.
Whether you want direct access to the ScitoSim platform or a structured report from our scientists, ScitoVation supports regulatory, product stewardship, litigation, and internal safety decisions.

THE PROBLEM
Scientific evidence is expanding. Decision timelines are shrinking.
Safety teams are being asked to evaluate more compounds, more data streams, and more regulatory questions with fewer resources and tighter timelines.
- Regulatory evidence is fragmented across sources.
- Manual review is slow, expensive, and difficult to reproduce.
- Transcriptomics, PBPK, and analyses from other studies often sit in separate workflows.
- Product stewardship and regulatory teams need clear, structured outputs that can be reviewed, challenged, updated, reproduced, and defended.

THE SCITOVATION SOLUTION
Expert judgment, strengthened by optimized computational workflows.
ScitoVation offers a focused approach in computational toxicology that combines expert judgment with workflows that automate repeatable analytical steps.
The result is continuity and acceleration: the scientific rigor ScitoVation is known for, now supported by structured workflows for literature synthesis, PBPK/qIVIVE, transcriptomics, mode-of-action analysis, and report generation.
Three ways we help clients reach stronger safety decisions:
Information
Synthesis

Using a traceable workflow and systematic approach, we can help clients reproduce any reports that require the synthesis of unstructured and structured data. This includes critical reviews, scoping reviews, impurity reports, post-market surveillance summaries, and recurring evidence updates.
For toxicology-related syntheses, one of the advantages we offer clients is augmenting these reports by translating data from in vitro or animal studies to human-equivalent values or complementing them with analyses of secondary data sets.
Dosimetry
(PBPK)

Transcriptomics and Mode of Action

Scientific credibility with modern delivery
- More than 100 peer-reviewed papers. See Publications
- Pioneer in submission of data to regulatory agencies to address human relevance of animal data or sensitivity of special populations. Learn More
- Proven experience supporting regulatory submissions on mode-of-action questions and agency-raised concerns.
- Legacy software tools and methods including PLETHEM and MoAViz.
- Strategic alliance with Integral Consulting for expanded risk-assessment support.
