About Us

We help clients assess chemical compound safety to develop safer and more effective pharmaceuticals, food ingredients, agricultural chemicals, commodity chemicals, and consumer products. At the frontline of next generation risk assessment (NGRA), we develop customized cell-based assays to determine safety, model chemical disposition in the body, and analyze and interpret genetic data. Our solutions save our clients time and money by bringing their products to market faster.

Latest News (See all)

Join us for our next webinar on July 13 at 11am ET.  Dr. Kareen Coulombe joins us to share her latest findings for assessing cardiac toxicity using a predictive 3D… Read more »

Mamta Behl, M.S, Ph.D, D.A.B.T, explores the latest developments in neurotoxicity models. This method uses a combination of in vitro, in vivo extrapolation, and exposure assessment to rapidly screen compounds with… Read more »

Featured Offering

ScitoVation and BioSpyder are excited to introduce our new transcriptomics analysis package, ScitoXpress™. ScitoXpress™ provides important information about points of departure (POD) and potential modes of action (MoA) for our clients’ compounds. ScitoXpress™ characterizes chemical risk cost-efficiently and rapidly.

Because changes in gene expression precede changes in phenotype, a robust transcriptomics package like ScitoXpress™ can provide answers at lower doses compared to disease or tumor endpoints are typical used in in vivo studies. ScitoXpress™ offers the additional advantages of:

  • Providing utility in guiding additional studies, resulting in cost- and time-savings
  • Being based on a rigorous scientific approach, applied by experts
  • Having the support of U.S. EPA


Who We Serve

By combining modern biological and computational methods, we help our clients develop safer and more effective pharmaceuticals, food ingredients, agricultural chemicals, commodity chemicals and consumer products.


Dr. Jean Orelien, CEO My passion is helping solve problems at the intersection of health, science, and technology. In other words, problems for which we can use science and technology to improve lives. With ScitoVation, our… Read more »

Patrick McMullen, Director of Computational Toxicology I have often joked that as a computational biologist in an applied field that has been slow to embrace bioinformatics, it is my goal… Read more »

As an advocate in PBPK modeling for risk assessment, I want to share with you the latest guidance from the Organization of Economic Cooperation and Development (OECD). I write a lot of reports on PBPK models for clients, and it makes a huge difference… Read more »